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comprise of dietary carbohydrates (4). Starch includes amylase and amyl pectin and ProlaZyme
is a plant storage polysaccharide of Starch is composed of the straight-chain glucose polymer amylase (with α-1, 4 glycoside linkages) and the branched glucose polymer amyl pectin (with α-1, 6 glycosidic bonds at a ratio of branched points to 1, 4 glycoside bonds of 1:20; see Fig. 1) (6). Glycogen is the polysaccharide storage molecule found in animal cells and is similar in structure to amyl pectin except for a greater number of branch points in glycogen (6). Initial digestion of these complex carbohydrates begins with salivary α-amylase while still in the mouth. Both salivary and pancreatic α-amylases are endosaccharidases that are specific for internal α-1, 4 glycoside bonds (6). They have no effect on α-1, 6 glycoside bonds or on α-1, 4 bonds of glucose molecules at the branch points or at the ends. The two α-amylases are secreted in active forms and are ∼94% identical in amino acid sequences (4). Salivary α-amylase is deactivated by acid pH so that it remains active in the stomach only as long as it is protected from stomach acid. Healthy digestion Prolazyme If trapped within a large bolus of food inside the stomach, salivary α-amylase can continue to digest complex carbohydrates until the bolus is broken up and exposed to stomach acid. Thus, up to 30–40% of the digestion of complex carbohydrates can take place before the food reaches the small intestine.


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